USP16 regulates castration-resistant prostate cancer cell proliferation by deubiquitinating and stablizing c-Myc

BACKGROUND: c-Myc, a well-established oncogene, plays an important role in the initiation and progression of various cancers, including prostate cancer. However, its mechanism in cancer cell remains largely unknown and whether there exist a deubiquitinase targeting c-Myc also remains elusive. METHOD...

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Detalles Bibliográficos
Autores principales: Ge, Jianchao, Yu, Wandong, Li, Junhong, Ma, Hangbin, Wang, Pengyu, Zhou, Yinghao, Wang, Yang, Zhang, Jun, Shi, Guowei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7866668/
https://www.ncbi.nlm.nih.gov/pubmed/33546726
http://dx.doi.org/10.1186/s13046-021-01843-8

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