Transcriptomic and metabolomic profiling reveal the p53-dependent benzeneacetic acid attenuation of silica‐induced epithelial–mesenchymal transition in human bronchial epithelial cells

BACKGROUND: Silica exposure underlies the development of silicosis, one of the most serious occupational hazards worldwide. We aimed to explore the interaction of the silica-induced epithelial–mesenchymal transition (EMT)-related transcripts with the cellular metabolism regulated by p53. METHODS: We...

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Detalles Bibliográficos
Autores principales: Ju, Zhao, Shao, Jianlin, Zhou, Meiling, Jin, Jing, Pan, Huiji, Ding, Ping, Huang, Ruixue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7866764/
https://www.ncbi.nlm.nih.gov/pubmed/33546743
http://dx.doi.org/10.1186/s13578-021-00545-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7866764/
https://www.ncbi.nlm.nih.gov/pubmed/33546743
http://dx.doi.org/10.1186/s13578-021-00545-0

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