Genetic and functional interaction network analysis reveals global enrichment of regulatory T cell genes influencing basal cell carcinoma susceptibility

BACKGROUND: Basal cell carcinoma (BCC) of the skin is the most common form of human cancer, with more than 90% of tumours presenting with clear genetic activation of the Hedgehog pathway. However, polygenic risk factors affecting mechanisms such as DNA repair and cell cycle checkpoints or which modu...

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Detalles Bibliográficos
Autores principales: Adolphe, Christelle, Xue, Angli, Fard, Atefeh Taherian, Genovesi, Laura A., Yang, Jian, Wainwright, Brandon J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7866769/
https://www.ncbi.nlm.nih.gov/pubmed/33549134
http://dx.doi.org/10.1186/s13073-021-00827-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7866769/
https://www.ncbi.nlm.nih.gov/pubmed/33549134
http://dx.doi.org/10.1186/s13073-021-00827-9

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