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The Effect of Neddylation Blockade on Slug-Dependent Cancer Cell Migration Is Regulated by p53 Mutation Status

SIMPLE SUMMARY: Neddylation is a process in which the small ubiquitin-like molecule NEDD8 is covalently conjugated to target proteins by sequential enzymatic reactions. Because neddylation plays critical roles in regulating cancer growth and migration, it is emerging as an effective therapeutic targ...

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Detalles Bibliográficos
Autores principales: Kim, Yelee, Park, Jun Bum, Fukuda, Junji, Watanabe, Masatoshi, Chun, Yang-Sook
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7866814/
https://www.ncbi.nlm.nih.gov/pubmed/33573293
http://dx.doi.org/10.3390/cancers13030531