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Transcriptomic profiling of SARS-CoV-2 infected human cell lines identifies HSP90 as target for COVID-19 therapy

Detailed knowledge of the molecular biology of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection is crucial for understanding of viral replication, host responses, and disease progression. Here, we report gene expression profiles of three SARS-CoV- and SARS-CoV-2-infected human...

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Detalles Bibliográficos
Autores principales: Wyler, Emanuel, Mösbauer, Kirstin, Franke, Vedran, Diag, Asija, Gottula, Lina Theresa, Arsiè, Roberto, Klironomos, Filippos, Koppstein, David, Hönzke, Katja, Ayoub, Salah, Buccitelli, Christopher, Hoffmann, Karen, Richter, Anja, Legnini, Ivano, Ivanov, Andranik, Mari, Tommaso, Del Giudice, Simone, Papies, Jan, Praktiknjo, Samantha, Meyer, Thomas F., Müller, Marcel Alexander, Niemeyer, Daniela, Hocke, Andreas, Selbach, Matthias, Akalin, Altuna, Rajewsky, Nikolaus, Drosten, Christian, Landthaler, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7866843/
https://www.ncbi.nlm.nih.gov/pubmed/33585804
http://dx.doi.org/10.1016/j.isci.2021.102151