A novel bicyclic 2,4-diaminopyrimidine inhibitor of Streptococcus suis dihydrofolate reductase

Streptococcus suis is a Gram-positive bacterial pathogen of pigs and an emerging zoonotic pathogen. It has become increasingly resistant to multiple classes of antibiotics. New drug candidates and knowledge of their targets are needed to combat antibiotic-resistant S. suis. In this study, the open-s...

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Detalles Bibliográficos
Autores principales: Songsungthong, Warangkhana, Prasopporn, Sunisa, Bohan, Louise, Srimanote, Potjanee, Leartsakulpanich, Ubolsree, Yongkiettrakul, Suganya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2021
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7866885/
https://www.ncbi.nlm.nih.gov/pubmed/33604179
http://dx.doi.org/10.7717/peerj.10743

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7866885/
https://www.ncbi.nlm.nih.gov/pubmed/33604179
http://dx.doi.org/10.7717/peerj.10743

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