In Vitro and In Vivo Antitumor Activity of Indolo[2,3-b] Quinolines, Natural Product Analogs from Neocryptolepine Alkaloid

Neocryptolepine (5-methyl-5H-indolo[2,3-b] quinoline) analogs were synthesized and evaluated in vitro and in vivo for their effect versus Ehrlich ascites carcinoma (EAC). The analogs showed stronger cytotoxic activity against EAC cells than the reference drug. The in vivo evaluation of the target co...

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Detalles Bibliográficos
Autores principales: Altwaijry, Najla, El-Ghlban, Samah, El Sayed, Ibrahim E.-T., El-Bahnsawye, Mohamed, Bayomi, Asmaa I., Samaka, Rehab M., Shaban, Elkhabiry, Elmongy, Elshaymaa I., El-Masry, Thanaa A., Ahmed, Hytham M. A., Attallah, Nashwah G. M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7867085/
https://www.ncbi.nlm.nih.gov/pubmed/33535575
http://dx.doi.org/10.3390/molecules26030754

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7867085/
https://www.ncbi.nlm.nih.gov/pubmed/33535575
http://dx.doi.org/10.3390/molecules26030754

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