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NMR Characterization of Angiogenin Variants and tRNA(Ala) Products Impacting Aberrant Protein Oligomerization

Protein oligomerization is key to countless physiological processes, but also to abnormal amyloid conformations implicated in over 25 mortal human diseases. Human Angiogenin (h-ANG), a ribonuclease A family member, produces RNA fragments that regulate ribosome formation, the creation of new blood ve...

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Detalles Bibliográficos
Autores principales: Fagagnini, Andrea, Garavís, Miguel, Gómez-Pinto, Irene, Fasoli, Sabrina, Gotte, Giovanni, Laurents, Douglas V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7867098/
https://www.ncbi.nlm.nih.gov/pubmed/33535464
http://dx.doi.org/10.3390/ijms22031439