Advances and Obstacles in Homology-Mediated Gene Editing of Hematopoietic Stem Cells

Homology-directed gene editing of hematopoietic stem and progenitor cells (HSPCs) is a promising strategy for the treatment of inherited blood disorders, obviating many of the limitations associated with viral vector-mediated gene therapies. The use of CRISPR/Cas9 or other programmable nucleases and...

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Detalles Bibliográficos
Autores principales: Salisbury-Ruf, Christi T., Larochelle, Andre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7867106/
https://www.ncbi.nlm.nih.gov/pubmed/33535527
http://dx.doi.org/10.3390/jcm10030513

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7867106/
https://www.ncbi.nlm.nih.gov/pubmed/33535527
http://dx.doi.org/10.3390/jcm10030513

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