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The Protein Secretome Is Altered in Rectal Cancer Tissue Compared to Normal Rectal Tissue, and Alterations in the Secretome Induce Enhanced Innate Immune Responses

SIMPLE SUMMARY: Rectal cancer occurs in the lower part of the bowel, and approximately half of all rectal cancer patients receive chemoradiotherapy before surgery. In ~22% of cases the tumour is eradicated, but the reasons for different response rates between patients are largely unknown. Inflammati...

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Detalles Bibliográficos
Autores principales: Heeran, Aisling B., Dunne, Margaret R., Morrissey, Maria E., Buckley, Croí E., Clarke, Niamh, Cannon, Aoife, Donlon, Noel E., Nugent, Timothy S., Durand, Michael, Dunne, Cara, Larkin, John O., Mehigan, Brian, McCormick, Paul, Lynam-Lennon, Niamh, O’Sullivan, Jacintha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7867296/
https://www.ncbi.nlm.nih.gov/pubmed/33540635
http://dx.doi.org/10.3390/cancers13030571