Cargando…
The Protein Secretome Is Altered in Rectal Cancer Tissue Compared to Normal Rectal Tissue, and Alterations in the Secretome Induce Enhanced Innate Immune Responses
SIMPLE SUMMARY: Rectal cancer occurs in the lower part of the bowel, and approximately half of all rectal cancer patients receive chemoradiotherapy before surgery. In ~22% of cases the tumour is eradicated, but the reasons for different response rates between patients are largely unknown. Inflammati...
Autores principales: | Heeran, Aisling B., Dunne, Margaret R., Morrissey, Maria E., Buckley, Croí E., Clarke, Niamh, Cannon, Aoife, Donlon, Noel E., Nugent, Timothy S., Durand, Michael, Dunne, Cara, Larkin, John O., Mehigan, Brian, McCormick, Paul, Lynam-Lennon, Niamh, O’Sullivan, Jacintha |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7867296/ https://www.ncbi.nlm.nih.gov/pubmed/33540635 http://dx.doi.org/10.3390/cancers13030571 |
Ejemplares similares
-
Radiation-induced Bystander Effect (RIBE) alters mitochondrial metabolism using a human rectal cancer ex vivo explant model
por: Heeran, Aisling B., et al.
Publicado: (2020) -
Energy Metabolism Is Altered in Radioresistant Rectal Cancer
por: Buckley, Croí E., et al.
Publicado: (2023) -
Metformin is a metabolic modulator and radiosensitiser in rectal cancer
por: Buckley, Croí E., et al.
Publicado: (2023) -
Opposing Immune-Metabolic Signature in Visceral Versus Subcutaneous Adipose Tissue in Patients with Adenocarcinoma of the Oesophagus and the Oesophagogastric Junction
por: Heeran, Aisling B., et al.
Publicado: (2021) -
Visceral adipose tissue secretome from early and late-stage oesophageal cancer patients differentially affects effector and regulatory T cells
por: Davern, Maria, et al.
Publicado: (2023)