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Stochastic asymmetric repartition of lytic machinery in dividing CD8(+) T cells generates heterogeneous killing behavior
Cytotoxic immune cells are endowed with a high degree of heterogeneity in their lytic function, but how this heterogeneity is generated is still an open question. We therefore investigated if human CD8(+) T cells could segregate their lytic components during telophase, using imaging flow cytometry,...
| Autores principales: | , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
eLife Sciences Publications, Ltd
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7867409/ https://www.ncbi.nlm.nih.gov/pubmed/33427199 http://dx.doi.org/10.7554/eLife.62691 |