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Spinal manifestations of CLN1 disease start during the early postnatal period

AIM: To understand the progression of CLN1 disease and develop effective therapies we need to characterize early sites of pathology. Therefore, we performed a comprehensive evaluation of the nature and timing of early CLN1 disease pathology in the spinal cord, which appears especially vulnerable, an...

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Detalles Bibliográficos
Autores principales: Nelvagal, H. R., Dearborn, J. T., Ostergaard, J. R., Sands, M. S., Cooper, J. D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7867600/
https://www.ncbi.nlm.nih.gov/pubmed/32841420
http://dx.doi.org/10.1111/nan.12658