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Role of next generation sequencing-based liquid biopsy in advanced non-small cell lung cancer patients treated with immune checkpoint inhibitors: impact of STK11, KRAS and TP53 mutations and co-mutations on outcome

BACKGROUND: Characterization of tumor-related genetic alterations is promising for the screening of new predictive markers in non-small cell lung cancer (NSCLC). Aim of the study was to evaluate prognostic and predictive role of most frequent tumor-associated genetic alterations detected in plasma b...

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Detalles Bibliográficos
Autores principales: Pavan, Alberto, Bragadin, Andrea Boscolo, Calvetti, Lorenzo, Ferro, Alessandra, Zulato, Elisabetta, Attili, Ilaria, Nardo, Giorgia, Dal Maso, Alessandro, Frega, Stefano, Menin, Andrea Giovanni, Fassan, Matteo, Calabrese, Fiorella, Pasello, Giulia, Guarneri, Valentina, Aprile, Giuseppe, Conte, PierFranco, Rosell, Rafael, Indraccolo, Stefano, Bonanno, Laura
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7867770/
https://www.ncbi.nlm.nih.gov/pubmed/33569305
http://dx.doi.org/10.21037/tlcr-20-674