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Role of next generation sequencing-based liquid biopsy in advanced non-small cell lung cancer patients treated with immune checkpoint inhibitors: impact of STK11, KRAS and TP53 mutations and co-mutations on outcome
BACKGROUND: Characterization of tumor-related genetic alterations is promising for the screening of new predictive markers in non-small cell lung cancer (NSCLC). Aim of the study was to evaluate prognostic and predictive role of most frequent tumor-associated genetic alterations detected in plasma b...
Autores principales: | Pavan, Alberto, Bragadin, Andrea Boscolo, Calvetti, Lorenzo, Ferro, Alessandra, Zulato, Elisabetta, Attili, Ilaria, Nardo, Giorgia, Dal Maso, Alessandro, Frega, Stefano, Menin, Andrea Giovanni, Fassan, Matteo, Calabrese, Fiorella, Pasello, Giulia, Guarneri, Valentina, Aprile, Giuseppe, Conte, PierFranco, Rosell, Rafael, Indraccolo, Stefano, Bonanno, Laura |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
AME Publishing Company
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7867770/ https://www.ncbi.nlm.nih.gov/pubmed/33569305 http://dx.doi.org/10.21037/tlcr-20-674 |
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