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High indoleamine-2,3-dioxygenase 1 (IDO) activity is linked to primary resistance to immunotherapy in non-small cell lung cancer (NSCLC)

BACKGROUND: Metabolic profiling in non-small cell lung cancer (NSCLC) may identify key metabolic vulnerabilities and shows enormous discovery potential. Preclinical studies showed that metabolic rewiring in cancer plays an essential role in modulation of immunotherapy response. However, this situati...

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Detalles Bibliográficos
Autores principales: Kocher, Florian, Amann, Arno, Zimmer, Kai, Geisler, Simon, Fuchs, Dietmar, Pichler, Renate, Wolf, Dominik, Kurz, Katharina, Seeber, Andreas, Pircher, Andreas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7867793/
https://www.ncbi.nlm.nih.gov/pubmed/33569314
http://dx.doi.org/10.21037/tlcr-20-380