Repressing PDCD4 activates JNK/ABCG2 pathway to induce chemoresistance to fluorouracil in colorectal cancer cells

BACKGROUND: Colorectal cancer (CRC) is the third major cause of cancer-related death worldwide, and fluorouracil (5-FU) is widely used in the treatment of CRC. However, acquired resistance to 5-FU has become an obstacle in the effective treatment of CRC. Adenosine triphosphate (ATP)-binding cassette...

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Detalles Bibliográficos
Autores principales: Hu, Lanlin, Liang, Yutong, Wu, Kelv, Wang, Caixia, Zhang, Tao, Peng, Rui, Zou, Fangdong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7867943/
https://www.ncbi.nlm.nih.gov/pubmed/33569416
http://dx.doi.org/10.21037/atm-20-4292

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7867943/
https://www.ncbi.nlm.nih.gov/pubmed/33569416
http://dx.doi.org/10.21037/atm-20-4292

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