Apurinic/apyrimidinic endonuclease 1/reduction-oxidation effector factor-1 (APE1) regulates the expression of NLR family pyrin domain containing 3 (NLRP3) inflammasome through modulating transcription factor NF-κB and promoting the secretion of inflammatory mediators in macrophages

BACKGROUND: Inflammatory mediators play an important role in the occurrence, development, and metastasis of tumors. The aim of the present study was to elucidate the effect of apurinic/apyrimidinic endonuclease 1/reduction-oxidation effector factor-1 (APE1) on inflammatory mediator secretion, which...

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Detalles Bibliográficos
Autores principales: Tang, Zheng, Wang, Ying, Wan, Yue, Xie, Yue, Li, Shujie, Tao, Dan, Wang, Can, Wu, Yong-Zhong, Sui, Jiang-Dong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7867945/
https://www.ncbi.nlm.nih.gov/pubmed/33569447
http://dx.doi.org/10.21037/atm-20-7752

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7867945/
https://www.ncbi.nlm.nih.gov/pubmed/33569447
http://dx.doi.org/10.21037/atm-20-7752

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