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Long non-coding RNA MT1DP interacts with miR-365 and induces apoptosis of nucleus pulposus cells by repressing NRF-2-induced anti-oxidation in lumbar disc herniation

BACKGROUND: This study investigated the effects of the long non-coding (lnc) RNA MT1DP on the apoptosis of nucleus pulposus (NP) cells. The interactions between MT1DP and the microRNA miR-365, and its effects on the anti-oxidant activity of nuclear factor erythroid 2-related factor 2 (NRF-2) were in...

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Detalles Bibliográficos
Autores principales: Liao, Zhuang-Wen, Fan, Zi-Wen, Huang, Yan, Liang, Cai-Yu, Liu, Chang, Huang, Shuai, Chen, Can-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7867946/
https://www.ncbi.nlm.nih.gov/pubmed/33569453
http://dx.doi.org/10.21037/atm-20-8123