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Synergistic Effects of TW-37 and ABT-263 on Renal Cell Carcinoma Cells

BACKGROUND: Renal cell carcinoma (RCC) is a common urological system malignancy lack of effective therapeutic options. Upregulation of the Bcl-2 proteins was correlated with poor prognosis of RCC, suggesting that BH-3 mimetics may be a promising treatment option. ABT-263 is a BH3 mimetic that posses...

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Detalles Bibliográficos
Autores principales: Yu, Rui, Lu, Yefen, Yu, Ren, Xie, Jianjun, Zhou, Shoujun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7868206/
https://www.ncbi.nlm.nih.gov/pubmed/33568941
http://dx.doi.org/10.2147/CMAR.S265788