NAA10 p.(N101K) disrupts N-terminal acetyltransferase complex NatA and is associated with developmental delay and hemihypertrophy

Nearly half of all human proteins are acetylated at their N-termini by the NatA N-terminal acetyltransferase complex. NAA10 is evolutionarily conserved as the catalytic subunit of NatA in complex with NAA15, but may also have NatA-independent functions. Several NAA10 variants are associated with gen...

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Detalles Bibliográficos
Autores principales: McTiernan, Nina, Gill, Harinder, Prada, Carlos E., Pachajoa, Harry, Lores, Juliana, Arnesen, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7868364/
https://www.ncbi.nlm.nih.gov/pubmed/32973342
http://dx.doi.org/10.1038/s41431-020-00728-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7868364/
https://www.ncbi.nlm.nih.gov/pubmed/32973342
http://dx.doi.org/10.1038/s41431-020-00728-2

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