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The Monocytes That Repopulate in Mice After Cyclophosphamide Treatment Acquire a Neutrophil Precursor Gene Signature and Immunosuppressive Activity

Cyclophosphamide (CTX) is a major component of the chemotherapy conditioning regimens used in the clinic to prepare cancer patients for hematopoietic stem cell transplantation or adoptive T cell therapy. Previous studies have shown that CTX given at nonmyeloablative doses in mice and patients leads...

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Detalles Bibliográficos
Autores principales: Ding, Zhi-Chun, Aboelella, Nada S., Bryan, Locke, Shi, Huidong, Zhou, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7868404/
https://www.ncbi.nlm.nih.gov/pubmed/33569051
http://dx.doi.org/10.3389/fimmu.2020.594540