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The Monocytes That Repopulate in Mice After Cyclophosphamide Treatment Acquire a Neutrophil Precursor Gene Signature and Immunosuppressive Activity
Cyclophosphamide (CTX) is a major component of the chemotherapy conditioning regimens used in the clinic to prepare cancer patients for hematopoietic stem cell transplantation or adoptive T cell therapy. Previous studies have shown that CTX given at nonmyeloablative doses in mice and patients leads...
Autores principales: | Ding, Zhi-Chun, Aboelella, Nada S., Bryan, Locke, Shi, Huidong, Zhou, Gang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7868404/ https://www.ncbi.nlm.nih.gov/pubmed/33569051 http://dx.doi.org/10.3389/fimmu.2020.594540 |
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