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Empirical and Rational Design of T Cell Receptor-Based Immunotherapies

The use of T cells reactive with intracellular tumor-associated or tumor-specific antigens has been a promising strategy for cancer immunotherapies in the past three decades, but the approach has been constrained by a limited understanding of the T cell receptor’s (TCR) complex functions and specifi...

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Detalles Bibliográficos
Autores principales: Jones, Heather F., Molvi, Zaki, Klatt, Martin G., Dao, Tao, Scheinberg, David A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7868419/
https://www.ncbi.nlm.nih.gov/pubmed/33569049
http://dx.doi.org/10.3389/fimmu.2020.585385