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Pain Control by Targeting Oxidized Phospholipids: Functions, Mechanisms, Perspectives

Within the lipidome oxidized phospholipids (OxPL) form a class of chemically highly reactive metabolites. OxPL are acutely produced in inflamed tissue and act as endogenous, proalgesic (pain-inducing) metabolites. They excite sensory, nociceptive neurons by activating transient receptor potential io...

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Detalles Bibliográficos
Autores principales: Oehler, Beatrice, Brack, Alexander, Blum, Robert, Rittner, Heike L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7868524/
https://www.ncbi.nlm.nih.gov/pubmed/33569042
http://dx.doi.org/10.3389/fendo.2020.613868