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The Human Leukocyte Antigen-DPB1 Degree of Compatibility Is Determined by Its Expression Level and Mismatch Permissiveness: A German Multicenter Analysis

T-cell epitope matching according to the TCE3 algorithm classifies HLA-DPB1 mismatches in permissive and non-permissive. This classification has been shown to be predictive for mortality and acute GvHD (aGvHD) events in large international cohorts. We retrospectively genotyped HLA-DPB1 in 3523 patie...

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Detalles Bibliográficos
Autores principales: Mytilineos, Daphne, Tsamadou, Chrysanthi, Neuchel, Christine, Platzbecker, Uwe, Bunjes, Donald, Schub, Natalie, Wagner-Drouet, Eva, Wulf, Gerald, Kröger, Nicolaus, Murawski, Niels, Einsele, Hermann, Schaefer-Eckart, Kerstin, Freitag, Sebastian, Casper, Jochen, Kaufmann, Martin, Dürholt, Mareike, Hertenstein, Bernd, Klein, Stefan, Ringhoffer, Mark, Mueller, Carlheinz R., Frank, Sandra, Schrezenmeier, Hubert, Fuerst, Daniel, Mytilineos, Joannis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7868530/
https://www.ncbi.nlm.nih.gov/pubmed/33569061
http://dx.doi.org/10.3389/fimmu.2020.614976