Metformin Reverses the Enhanced Myocardial SR/ER–Mitochondria Interaction and Impaired Complex I-Driven Respiration in Dystrophin-Deficient Mice

Besides skeletal muscle dysfunction, Duchenne muscular dystrophy (DMD) exhibits a progressive cardiomyopathy characterized by an impaired calcium (Ca(2+)) homeostasis and a mitochondrial dysfunction. Here we aimed to determine whether sarco-endoplasmic reticulum (SR/ER)–mitochondria interactions and...

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Detalles Bibliográficos
Autores principales: Angebault, Claire, Panel, Mathieu, Lacôte, Mathilde, Rieusset, Jennifer, Lacampagne, Alain, Fauconnier, Jérémy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cell and Developmental Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7868535/
https://www.ncbi.nlm.nih.gov/pubmed/33569379
http://dx.doi.org/10.3389/fcell.2020.609493

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7868535/
https://www.ncbi.nlm.nih.gov/pubmed/33569379
http://dx.doi.org/10.3389/fcell.2020.609493

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