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Protective Effect of the α7 Nicotinic Receptor Agonist PNU-282987 on Dopaminergic Neurons Against 6-Hydroxydopamine, Regulating Anti-neuroinflammatory and the Immune Balance Pathways in Rat

Neuroinflammation and inner immune dysfunction are increasingly accepted as important components of the etiopathogenesis of Parkinson’s disease (PD). According to emerging evidence, a7 nicotinic acetylcholine receptor (α7nAChR), a ligand-gated ion channel, plays an important role in inflammatory rea...

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Detalles Bibliográficos
Autores principales: Jiang, Ying, Ma, Huizi, Wang, Xuemei, Wang, Zhan, Yang, Yaqin, Li, Longling, Feng, Tao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7868536/
https://www.ncbi.nlm.nih.gov/pubmed/33568987
http://dx.doi.org/10.3389/fnagi.2020.606927