Chrysophanol Exerts Anti-inflammatory Activity by Targeting Histone Deacetylase 3 Through the High Mobility Group Protein 1-Nuclear Transcription Factor-Kappa B Signaling Pathway in vivo and in vitro

Chrysophanol (Chr) is the main monomer isolated from Rheum rhabarbarum. This study aimed to identify the potential in vitro and in vivo cytoprotective effects of Chr on lipopolysaccharide (LPS)-triggered acute lung injury (ALI). We used an ALI-murine model and constructed an inflammatory macrophage...

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Detalles Bibliográficos
Autores principales: Wen, Quan, Lau, Ngaikeung, Weng, Huandi, Ye, Peng, Du, Shaohui, Li, Chun, Lv, Jianping, Li, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Bioengineering and Biotechnology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7868569/
https://www.ncbi.nlm.nih.gov/pubmed/33569375
http://dx.doi.org/10.3389/fbioe.2020.623866

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7868569/
https://www.ncbi.nlm.nih.gov/pubmed/33569375
http://dx.doi.org/10.3389/fbioe.2020.623866

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