Blocking the IGF2BP1-promoted glucose metabolism of colon cancer cells via direct de-stabilizing mRNA of the LDHA enhances anticancer effects

Colorectal cancer (CRC) is a commonly diagnosed cancer with poor prognosis and high mortality rate. Hyperthermia (HT) is an adjunctive therapy to enhance the antitumor effects of traditional chemo- or radio- therapy. Here, we report that a cluster of essential regulator genes and speed-limit enzymes...

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Detalles Bibliográficos
Autores principales: Zhang, Xiang-liang, Li, Ke-jun, Feng, Jin-xin, Liu, Gao-jie, Feng, Yan-lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society of Gene & Cell Therapy 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7868688/
https://www.ncbi.nlm.nih.gov/pubmed/33614233
http://dx.doi.org/10.1016/j.omtn.2020.12.020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7868688/
https://www.ncbi.nlm.nih.gov/pubmed/33614233
http://dx.doi.org/10.1016/j.omtn.2020.12.020

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