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Role of ALDH2 in Hepatic Disorders: Gene Polymorphism and Disease Pathogenesis

Aldehyde dehydrogenase 2 (ALDH2) is a key enzyme of alcohol metabolism and it is involved in the cellular mechanism of alcohol liver disease. ALDH2 gene mutations exist in about 8% of the world’s population, with the incidence reaching 45% in East Asia. The mutations will result in impairment of enz...

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Detalles Bibliográficos
Autores principales: Wang, Qiaoling, Chang, Binxia, Li, Xiaoyan, Zou, Zhengsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: XIA & HE Publishing Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7868706/
https://www.ncbi.nlm.nih.gov/pubmed/33604259
http://dx.doi.org/10.14218/JCTH.2020.00104