Structural flexibility of the tetanus neurotoxin revealed by crystallographic and solution scattering analyses

Although the tetanus neurotoxin (TeNT) delivers its protease domain (LC) across the synaptic vesicle lumen into the cytosol via its receptor binding domain (H(C)) and translocation domain (H(N)), the molecular mechanism coordinating this membrane translocation remains unresolved. Here, we report the...

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Detalles Bibliográficos
Autores principales: Zhang, Chun-ming, Imoto, Yoshihiro, Hikima, Takaaki, Inoue, Tsuyoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7868712/
https://www.ncbi.nlm.nih.gov/pubmed/33598655
http://dx.doi.org/10.1016/j.yjsbx.2021.100045

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7868712/
https://www.ncbi.nlm.nih.gov/pubmed/33598655
http://dx.doi.org/10.1016/j.yjsbx.2021.100045

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