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Structural flexibility of the tetanus neurotoxin revealed by crystallographic and solution scattering analyses
Although the tetanus neurotoxin (TeNT) delivers its protease domain (LC) across the synaptic vesicle lumen into the cytosol via its receptor binding domain (H(C)) and translocation domain (H(N)), the molecular mechanism coordinating this membrane translocation remains unresolved. Here, we report the...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Elsevier
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7868712/ https://www.ncbi.nlm.nih.gov/pubmed/33598655 http://dx.doi.org/10.1016/j.yjsbx.2021.100045 |