Pathological RANK signaling in B cells drives autoimmunity and chronic lymphocytic leukemia

Clinical evidence suggests alterations in receptor activator of NF-κB (RANK) signaling are key contributors to B cell autoimmunity and malignancy, but the pathophysiological consequences of aberrant B cell–intrinsic RANK signaling remain unknown. We generated mice that express a human lymphoma–deriv...

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Detalles Bibliográficos
Autores principales: Alankus, Begüm, Ecker, Veronika, Vahl, Nathalie, Braun, Martina, Weichert, Wilko, Macher-Göppinger, Stephan, Gehring, Torben, Neumayer, Tanja, Zenz, Thorsten, Buchner, Maike, Ruland, Jürgen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Rockefeller University Press 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7868734/
https://www.ncbi.nlm.nih.gov/pubmed/33075129
http://dx.doi.org/10.1084/jem.20200517

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7868734/
https://www.ncbi.nlm.nih.gov/pubmed/33075129
http://dx.doi.org/10.1084/jem.20200517

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