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Detection of Ca(2+) transients near ryanodine receptors by targeting fluorescent Ca(2+) sensors to the triad
In intact muscle fibers, functional properties of ryanodine receptor (RYR)–mediated sarcoplasmic reticulum (SR) Ca(2+) release triggered by activation of the voltage sensor Ca(V)1.1 have so far essentially been addressed with diffusible Ca(2+)-sensitive dyes. Here, we used a domain (T306) of the pro...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Rockefeller University Press
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7868779/ https://www.ncbi.nlm.nih.gov/pubmed/33538764 http://dx.doi.org/10.1085/jgp.202012592 |