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Modulation of hypochlorous acid (HOCl) induced damage to vascular smooth muscle cells by thiocyanate and selenium analogues

The production of hypochlorous acid (HOCl) by myeloperoxidase (MPO) plays a key role in immune defense, but also induces host tissue damage, particularly in chronic inflammatory pathologies, including atherosclerosis. This has sparked interest in the development of therapeutic approaches that decrea...

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Detalles Bibliográficos
Autores principales: Flouda, Konstantina, Gammelgaard, Bente, Davies, Michael J., Hawkins, Clare L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7868818/
https://www.ncbi.nlm.nih.gov/pubmed/33550113
http://dx.doi.org/10.1016/j.redox.2021.101873