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Carboxypeptidase B blocks ex vivo activation of the anaphylatoxin-neutrophil extracellular trap axis in neutrophils from COVID-19 patients

BACKGROUND: Thrombosis and coagulopathy are highly prevalent in critically ill patients with COVID-19 and increase the risk of death. Immunothrombosis has recently been demonstrated to contribute to the thrombotic events in COVID-19 patients with coagulopathy. As the primary components of immunothro...

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Detalles Bibliográficos
Autores principales: Zhang, Yue, Han, Kai, Du, Chunjing, Li, Rui, Liu, Jingyuan, Zeng, Hui, Zhu, Liuluan, Li, Ang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7868871/
https://www.ncbi.nlm.nih.gov/pubmed/33557911
http://dx.doi.org/10.1186/s13054-021-03482-z