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The aging proteostasis decline: From nematode to human

The aging proteostasis decline manifests in a failure of aging cells and organisms to properly respond to proteotoxic challenges. This proteostasis collapse has long been considered a hallmark of aging in nematodes, and has recently been shown to occur also in human cells upon entry to senescence, o...

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Detalles Bibliográficos
Autores principales: Meller, Anatoly, Shalgi, Reut
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Academic Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7868887/
https://www.ncbi.nlm.nih.gov/pubmed/33434530
http://dx.doi.org/10.1016/j.yexcr.2021.112474