Cargando…
The aging proteostasis decline: From nematode to human
The aging proteostasis decline manifests in a failure of aging cells and organisms to properly respond to proteotoxic challenges. This proteostasis collapse has long been considered a hallmark of aging in nematodes, and has recently been shown to occur also in human cells upon entry to senescence, o...
Autores principales: | Meller, Anatoly, Shalgi, Reut |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academic Press
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7868887/ https://www.ncbi.nlm.nih.gov/pubmed/33434530 http://dx.doi.org/10.1016/j.yexcr.2021.112474 |
Ejemplares similares
-
Cellular proteostasis decline in human senescence
por: Sabath, Niv, et al.
Publicado: (2020) -
Amino Acid Biosynthesis Regulation during Endoplasmic Reticulum Stress Is Coupled to Protein Expression Demands
por: Gonen, Nir, et al.
Publicado: (2019) -
Stress-induced transcriptional readthrough into neighboring genes is linked to intron retention
por: Hadar, Shani, et al.
Publicado: (2022) -
Cellular proteostasis decline in human senescence
por: Montague-Cardoso, Karli
Publicado: (2021) -
Differential roles for DNAJ isoforms in HTT-polyQ and FUS aggregation modulation revealed by chaperone screens
por: Rozales, Kinneret, et al.
Publicado: (2022)