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Senescence associated long non-coding RNA 1 regulates cigarette smoke-induced senescence of type II alveolar epithelial cells through sirtuin-1 signaling

OBJECTIVE: The primary aim of our study was to explore the mechanisms through which long non-coding RNA (lncRNA)-mediated sirtuin-1 (SIRT1) signaling regulates type II alveolar epithelial cell (AECII) senescence induced by a cigarette smoke-media suspension (CSM). METHODS: Pharmacological SIRT1 acti...

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Detalles Bibliográficos
Autores principales: Yuan, Dong, Liu, Yuanshun, Li, Mengyu, Zhou, Hongbin, Cao, Liming, Zhang, Xiaoqin, Li, Yaqing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7869169/
https://www.ncbi.nlm.nih.gov/pubmed/33535826
http://dx.doi.org/10.1177/0300060520986049