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MAR1 suppresses inflammatory response in LPS-induced RAW 264.7 macrophages and human primary peripheral blood mononuclear cells via the SIRT1/PGC-1α/PPAR-γ pathway

BACKGROUND: Sepsis is a complex syndrome characterized by a dysregulated inflammatory response to systemic infection and leads to shock, multiple organ failure and death especially if not recognized early and treated promptly. Previous studies have suggested Maresin 1 (MAR1) can alleviate systemic i...

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Detalles Bibliográficos
Autores principales: Wang, Wei, Xu, Rong-Li, He, Ping, Chen, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7869219/
https://www.ncbi.nlm.nih.gov/pubmed/33557833
http://dx.doi.org/10.1186/s12950-021-00271-x