What is the prospect of indoleamine 2,3-dioxygenase 1 inhibition in cancer? Extrapolation from the past

Indoleamine 2,3-dioxygenase 1 (IDO1), a monomeric heme-containing enzyme, catalyzes the first and rate-limiting step in the kynurenine pathway of tryptophan metabolism, which plays an important role in immunity and neuronal function. Its implication in different pathophysiologic processes including...

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Detalles Bibliográficos
Autores principales: Yao, Yu, Liang, Heng, Fang, Xin, Zhang, Shengnan, Xing, Zikang, Shi, Lei, Kuang, Chunxiang, Seliger, Barbara, Yang, Qing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7869231/
https://www.ncbi.nlm.nih.gov/pubmed/33557876
http://dx.doi.org/10.1186/s13046-021-01847-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7869231/
https://www.ncbi.nlm.nih.gov/pubmed/33557876
http://dx.doi.org/10.1186/s13046-021-01847-4

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