Cargando…

Cross-talk of four types of RNA modification writers defines tumor microenvironment and pharmacogenomic landscape in colorectal cancer

BACKGROUND: The four major RNA adenosine modifications, i.e., m(6)A, m(1)A, alternative polyadenylation, and adenosine-to-inosine RNA editing, are mediated mostly by the “writer” enzymes and constitute critical mechanisms of epigenetic regulation in immune response and tumorigenesis. However, the cr...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Huifang, Yao, Jiameng, Bao, Rujuan, Dong, Yu, Zhang, Ting, Du, Yanhua, Wang, Gaoyang, Ni, Duan, Xun, Zhenzhen, Niu, Xiaoyin, Ye, Youqiong, Li, Hua-Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7869236/
https://www.ncbi.nlm.nih.gov/pubmed/33557837
http://dx.doi.org/10.1186/s12943-021-01322-w