Cross-talk of four types of RNA modification writers defines tumor microenvironment and pharmacogenomic landscape in colorectal cancer

BACKGROUND: The four major RNA adenosine modifications, i.e., m(6)A, m(1)A, alternative polyadenylation, and adenosine-to-inosine RNA editing, are mediated mostly by the “writer” enzymes and constitute critical mechanisms of epigenetic regulation in immune response and tumorigenesis. However, the cr...

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Detalles Bibliográficos
Autores principales: Chen, Huifang, Yao, Jiameng, Bao, Rujuan, Dong, Yu, Zhang, Ting, Du, Yanhua, Wang, Gaoyang, Ni, Duan, Xun, Zhenzhen, Niu, Xiaoyin, Ye, Youqiong, Li, Hua-Bing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7869236/
https://www.ncbi.nlm.nih.gov/pubmed/33557837
http://dx.doi.org/10.1186/s12943-021-01322-w

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