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Effect of ABCA1 promoter methylation on premature coronary artery disease and its relationship with inflammation

BACKGROUND: ATP-binding cassette transporter A1 (ABCA1) plays a major role in high-density lipoprotein (HDL) metabolism and reverse cholesterol transport (RCT) and exerts anti-inflammatory effects. Increased ABCA1 promoter methylation level may result in the progression of coronary artery disease. T...

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Detalles Bibliográficos
Autores principales: An, Fang, Liu, Chao, Wang, Xiujuan, Li, Tan, Fu, Hao, Bao, Buhe, Cong, Hongliang, Zhao, Jihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7869242/
https://www.ncbi.nlm.nih.gov/pubmed/33557767
http://dx.doi.org/10.1186/s12872-021-01894-x