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Structure-aware protein solubility prediction from sequence through graph convolutional network and predicted contact map
Protein solubility is significant in producing new soluble proteins that can reduce the cost of biocatalysts or therapeutic agents. Therefore, a computational model is highly desired to accurately predict protein solubility from the amino acid sequence. Many methods have been developed, but they are...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7869490/ https://www.ncbi.nlm.nih.gov/pubmed/33557952 http://dx.doi.org/10.1186/s13321-021-00488-1 |