Mind the translational gap: using iPS cell models to bridge from genetic discoveries to perturbed pathways and therapeutic targets

Autism spectrum disorder (ASD) comprises a group of neurodevelopmental disorders characterized by impaired social interactions as well as the presentation of restrictive and repetitive behaviors. ASD is highly heritable but genetically heterogenous with both common and rare genetic variants collabor...

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Detalles Bibliográficos
Autores principales: Pintacuda, Greta, Martín, Jacqueline M., Eggan, Kevin C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7869517/
https://www.ncbi.nlm.nih.gov/pubmed/33557935
http://dx.doi.org/10.1186/s13229-021-00417-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7869517/
https://www.ncbi.nlm.nih.gov/pubmed/33557935
http://dx.doi.org/10.1186/s13229-021-00417-x

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