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Mind the translational gap: using iPS cell models to bridge from genetic discoveries to perturbed pathways and therapeutic targets
Autism spectrum disorder (ASD) comprises a group of neurodevelopmental disorders characterized by impaired social interactions as well as the presentation of restrictive and repetitive behaviors. ASD is highly heritable but genetically heterogenous with both common and rare genetic variants collabor...
Autores principales: | Pintacuda, Greta, Martín, Jacqueline M., Eggan, Kevin C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7869517/ https://www.ncbi.nlm.nih.gov/pubmed/33557935 http://dx.doi.org/10.1186/s13229-021-00417-x |
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