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2-Chloro-3-nitro-5-(tri­fluoro­meth­yl)benzoic acid and -benzamide: structural characterization of two precursors for anti­tubercular benzo­thia­zinones

8-Nitro-1,3-benzo­thia­zin-4-ones are a promising class of new anti­tubercular agents, two candidates of which, namely BTZ043 and PBTZ169 (INN: macozinone), have reached clinical trials. The crystal and mol­ecular structures of two synthetic precursors, 2-chloro-3-nitro-5-(tri­fluoro­meth­yl)benzoic...

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Detalles Bibliográficos
Autores principales: Richter, Adrian, Goddard, Richard, Schlegel, Tom, Imming, Peter, Seidel, Rüdiger W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7869535/
https://www.ncbi.nlm.nih.gov/pubmed/33614143
http://dx.doi.org/10.1107/S2056989021000517