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Drug repurposing for COVID-19 via knowledge graph completion

OBJECTIVE: To discover candidate drugs to repurpose for COVID-19 using literature-derived knowledge and knowledge graph completion methods. METHODS: We propose a novel, integrative, and neural network-based literature-based discovery (LBD) approach to identify drug candidates from PubMed and other C...

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Detalles Bibliográficos
Autores principales: Zhang, Rui, Hristovski, Dimitar, Schutte, Dalton, Kastrin, Andrej, Fiszman, Marcelo, Kilicoglu, Halil
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7869625/
https://www.ncbi.nlm.nih.gov/pubmed/33571675
http://dx.doi.org/10.1016/j.jbi.2021.103696